USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation.
Correct segregation of the mitotic chromosomes into daughter cells is a highly regulated process critical HIMALAYAN SALT FINE to safeguard genome stability.During M phase the spindle assembly checkpoint (SAC) ensures that all kinetochores are correctly attached before its inactivation allows progression into anaphase.Upon SAC inactivation, the anap